McMaster Researcher Makes One of the Top Discoveries According to The New York Times

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Hamilton Business Review

December 24, 2024
John Stokes, a bearded tattooed man in a hoodie and a lab coat, with glasses and a toque, smiling in his lab.

In a celebration of transformative discoveries of 2023, The New York Times calls McMaster researcher Jon Stokes’ innovative work on antibiotic resistance one of the year’s most important scientific and technological advances.

The article, which includes groundbreaking discoveries in the field of kidney transplants and momentous technological feats like NASA’s James Webb Telescope, specifically highlights Stokes’ use of artificial intelligence to develop a treatment for a deadly, drug-resistant pathogen that impacts vulnerable hospital patients.

Acinetobacter baumannii, identified by the World Health Organization as one of the world’s most dangerous antibiotic-resistant bacteria, is a pathogen capable of causing pneumonia, meningitis and other infections, all of which can lead to death.

Stokes’ team used an artificial intelligence algorithm to predict new structural classes of antibacterial molecules, and identified a new antibacterial compound named abaucin.

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